How to Change the Overview Box border

Yes, you can redefine the whole Overview.box. But I found that this worked, just as the 2014 forum post said:

      myOverview =
        $(go.Overview, "myOverviewDiv",
          {
            observed: myDiagram,
            contentAlignment: go.Spot.Center
          });
      myOverview.box.elt(0).stroke = "orange";